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Cell mass state discrimination technique, image processing program and image processing apparatus using the technique, and cell mass production method
Cell mass state discrimination technique, image processing program and image processing apparatus using the technique, and cell mass production method
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机译:细胞质量状态鉴别技术,使用该技术的图像处理程序和图像处理装置以及细胞大量生产方法
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摘要
Provided is means for determining and outputting, from time lapse images, the state of change of a cell aggregation toward becoming multi-layered. An image processing program (GP) is provided with: a step (S10) for obtaining time lapse images; a step (S20) for extracting a cell aggregation from each of the obtained images; a step (S50) for calculating, for the entire region of the cell aggregation, the spatial distribution in pixel values and temporal change in pixel values of a small region in the extracted cell aggregation; a step (S70) for determining the state of change of the cell aggregation toward becoming multi-layered, on the basis of the calculated spatial distribution and time lapse change of pixel values; and a step (S80) for outputting the results of the determination. The image processing program (GP) is configured so as to determine and output, from time lapse images, the state of change of the cell aggregation toward becoming multi-layered.
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