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Perfusion mechanism for analyzing thrombotic-ischemic and bleeding lesions, apparatus using the perfusion mechanism, and method thereof

机译:用于分析血栓性缺血性和出血性病变的灌注机理,使用该灌注机理的设备及其方法

摘要

Thrombotic—A perfusion mechanism for dynamically analyzing ischemia and hemorrhage lesions, comprising at least one microchannel (54) connectable to the circuit (13), within the circuit (13) Biological fluids, such as blood or other blood-related fluids, whether animal or human, and mixtures of the fluids and additives, or non-living Fluids, such as biological fluids, and try to analyze, such as cell adhesion matrices, to simulate damaged vascular surfaces and to reproduce hemostasis and processes A perfusion mechanism in which at least one reaction substrate is present. The perfusion chamber is made of a material that allows optical acquisition of fluorescent fluids and / or visible light of a fluid flow image or video in at least one microchannel (54). [Selection] Figure 1
机译:血栓形成性-一种用于动态分析局部缺血和出血损伤的灌注机制,包括至少一个可连接至回路(13)的微通道(54),位于回路(13)内。生物液体,例如血液或其他与血液有关的液体,无论是动物或人类,以及液体和添加剂或非生物液体(例如生物液体)的混合物,并尝试进行分析(例如细胞粘附基质)以模拟受损的血管表面并重现止血和过程一种灌注机制,其中存在至少一种反应底物。灌注室由允许在至少一个微通道(54)中光学采集荧光流体和/或流体流动图像或视频的可见光的材料制成。 [选择]图1

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