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evaluation method of properties of the stratum corneum of the skin

机译:皮肤角质层特性的评价方法

摘要

PROBLEM TO BE SOLVED: To provide a method capable of noninvasively, quickly and easily evaluating a property of a horny layer of the skin.SOLUTION: The evaluation method of the property of the horny layer of the skin in the present invention includes: measuring an infrared absorption spectrum by infrared spectroscopy with the horny layer of the skin of a human being as an object; dividing a superimposed peak of an α helix and a random coil and a peak of a &bgr; sheet from the peak of an amide I absorption band derived from a protein secondary structure in the infrared absorption spectrum; calculating an area of the superimposed peak of the α helix and the random coil and a peak area of the &bgr; sheet and calculating a peak area ratio &bgr;/α defined by [the peak area of the &bgr; sheet]/[the area of the superimposed peak of the α helix and the random coil]; and evaluating the property of the horny layer of the skin with the value of the calculated ratio &bgr;/α as an index.
机译:解决的问题:提供一种能够无创,快速且容易地评价皮肤的角质层的性质的方法。解决方案:本发明中的皮肤的角质层的性质的评价方法包括:测量皮肤的角质层的性质。通过红外光谱法以人的皮肤的角质层为对象的红外吸收光谱;划分α的叠加峰螺旋和随机线圈以及abb的峰值从红外吸收光谱中源自蛋白质二级结构的酰胺I吸收带的峰开始折叠;计算α的叠加峰的面积。螺旋和无规线圈以及&bgr;的峰面积并计算峰面积比&bgr; /α由[&bgr;的峰面积片] / [α的叠加峰的面积;螺旋和随机线圈];并用计算出的比值&bgr; /α的值评估皮肤的角质层的特性。作为索引。

著录项

  • 公开/公告号JP5756370B2

    专利类型

  • 公开/公告日2015-07-29

    原文格式PDF

  • 申请/专利权人 花王株式会社;

    申请/专利号JP20110180062

  • 发明设计人 高田 真吾;宮内 勇貴;内藤 智;

    申请日2011-08-22

  • 分类号G01N21/3563;G01N21/17;

  • 国家 JP

  • 入库时间 2022-08-21 15:30:12

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