首页> 外国专利> N-substituted aminobenzocycloheptene, aminotetralin, aminoindane and phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy

N-substituted aminobenzocycloheptene, aminotetralin, aminoindane and phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy

机译:N-取代的氨基苯并环庚烯,氨基四氢萘,氨基茚满和苯烷基胺衍生物,含有它们的药物组合物及其在治疗中的用途

摘要

The present invention relates to N-substituted aminobenzocycloheptene, aminotetralin, aminoindane and phenalkylamine derivatives of formula (I), (II), (III) or (IV), or physiologically acceptable salts thereof. . The present invention relates to pharmaceutical compositions comprising such N-substituted aminobenzocycloheptene, aminotetralin, aminoindane and phenalkylamine derivatives, and such N-substituted aminobenzocycloheptene, aminotetralin for therapeutic purposes. And the use of aminoindane and phenalkylamine derivatives. N-substituted aminobenzocycloheptene, aminotetralin, aminoindane and phenalkylamine derivatives are GlyT1 inhibitors.
机译:本发明涉及式(I),(II),(III)或(IV)的N-取代的氨基苯并环庚烯,氨基四氢萘,氨基茚满和苯烷基胺衍生物,或其生理上可接受的盐。 。本发明涉及药物组合物,其包含用于治疗目的的此类N-取代的氨基苯并环庚烯,氨基四氢萘,氨基茚满和苯烷基胺衍生物,以及此类N-取代的氨基苯并环庚烯,氨基四氢萘。并使用氨基茚满和苯烷基胺衍生物。 N-取代的氨基苯并环庚烯,氨基四氢萘,氨基茚满和苯烷基胺衍生物是GlyT1抑制剂。

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