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Lumen formation inhibitor of vascular endothelial cells
Lumen formation inhibitor of vascular endothelial cells
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机译:血管内皮细胞的管腔形成抑制剂
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摘要
PROBLEM TO BE SOLVED: To provide a lumen formation inhibitor which is characterized by not substantially inhibiting the growth of an endothelial cell with a deoxy sugar derivative or a sugar alcohol derivative as an effective component.;SOLUTION: There is provided the lumen forming inhibitor which is characterized in that it does not substantially inhibit the growth of the endothelial cell with the deoxy sugar derivative or the sugar alcohol derivative except for 1, 5-Anhydro-2-deoxy-D-arabino-hexitol (ADAH, formula (4)) as the effective component. Particularly, D-Glucal (formula (1)) as the sugar alcohol derivative, or 2, 3-Dideoxy-D-erythro-hexose(DEH, formula (2)) as the deoxy sugar derivative, or Alkyl 2, 3-dideoxy-D-erythro-hexapyranoside (ADEH, formula (5)) is used as the effective component. (In the formula (5), R denotes a 1-5C alkyl group).;COPYRIGHT: (C)2012,JPO&INPIT
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