首页> 外国专利> N-((1-BENZYL-1H-1,2,3-TRIAZOL-4-YL)METHYL)ARYLAMIDE COMPOUNDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF

N-((1-BENZYL-1H-1,2,3-TRIAZOL-4-YL)METHYL)ARYLAMIDE COMPOUNDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF

机译：N-（（1-苄基-1H-1,2,3-三唑-4-基）甲基）芳基酰胺化合物作为潜在的抗癌剂及其制备方法

页面导航

摘要
著录项
相似文献

摘要

The present invention provides a compound of general formula 1, useful as potential anticancer agents against human cancer cell lines and process for the preparation thereof.; embedded image

R₁=H, 4-F, 4-Cl, 4-Br, 4-OMe, 3-F, 2,4-diOMe, 2,5-diOMe, 3,5-diOMe, 3,4,5-triOMe, 4-ClBn R₂=3-OPh, 4-F, 4-Cl, 4-Br, 4-OMe, 3,5-diOMe

机译：本发明提供了通式1的化合物，可用作潜在的抗人癌细胞系的抗癌剂及其制备方法。 “嵌入式图像”

R _{1 = H，4-F，4-Cl，4-Br，4-OMe，3-F，2,4 -diOMe，2,5-diOMe，3,5-diOMe，3,4,5-triOMe，4-ClBn R _{2 = 3-OPh，4-F，4-Cl，4-Br，4-OMe，3,5-diOMe}}

著录项

公开/公告号US2015166507A1

专利类型
公开/公告日2015-06-18

原文格式PDF
申请/专利权人 COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH;
展开▼

申请/专利号US201414569173
发明设计人 VANGALA SAIDI REDDY;BUDAGANABOYINA PRASAD;NARRIKOLLA VENKATA SUBBA REDDY;AHMED KAMAL;VADITHE LAKSHMA NAYAK;
展开▼

申请日2014-12-12
分类号C07D401/12;
国家 US
入库时间 2022-08-21 15:26:48

相似文献

专利
外文文献
中文文献

1. Effects of different cue positions on evoked potentials in the cerebral cortex during global and local processing of compound stimuli A study of event-related potential [J] . Xuemin Zhang, Yongna LiO, Siyu Bai, 中国神经再生研究：英文版 . 2009,第011期

2. Effects of different cue positions on evoked potentials in the cerebral cortex during global and local processing of compound stimuli A study of event-related potential [J] . Xuemin Zhang, Yongna Li, Siyu Bai, 中国神经再生研究（英文版） . 2009,第011期

3. Synthesis and evaluation of N-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl) nicotinamides as potential anticancer agents that inhibit tubulin polymerization [J] . KamalA., ReddyN.V.S., NayakV.L., Bioorganic and medicinal chemistry . 2014,第13期

4. N-((1-Benzyl-1H-1,2,3-triazol-4-yl)methyl)arylamide as a New Scaffold that Provides Rapid Access to Antimicrotubule Agents: Synthesis and Evaluation of Antiproliferative Activity Against Select Cancer Cell Lines [J] . Stefely JA, Palchaudhuri R, Miller PA, Journal of Medicinal Chemistry . 2010,第8期

5. Discovery of (+)-N-(3-aminopropyl)-N-[1-(5-benzyl-3-methyl-4-oxo-[1,2] thiazolo[5,4- d ]pyrimidin-6-yl)-2-methylpropyl]-4-methylbenzamide (AZD4877), a kinesin spindle protein inhibitor and potential anticancer agent [J] . Theoclitou M.-E., Aquila B., Block M.H., Journal of Medicinal Chemistry . 2011,第19期

6. Multispectroscopic Investigation of the Interaction of BSA and DNA with the anticancer drug,N-(6-ferrocenyl-2-naphthoyl)-gamma-amino butyric acid Methyl ester [C] . S.R. Rajina, Geethu Sudhi, P. Austin, International Conference on Condensed Matter and Applied Physics . 2017

7. In search of selective and potent Golgi alpha-mannosidase II inhibitors as potential anticancer agents: Synthesis of 3-substituted-swainsonine analogs and preparation of immobilized swainsonine analogs on solid support. [D] . Guo, Luyi. 2003

8. N-((1-Benzyl-1H-123-triazol-4-yl)methyl)arylamide as a New Scaffold that Provides Rapid Access to Antimicrotubule Agents: Synthesis and Evaluation of Antiproliferative Activity Against Select Cancer Cell Lines [O] . Jonathan A. Stefely, Rahul Palchaudhuri, Patricia A. Miller, -1

9. N-((1-Benzyl-1H-1,2,3-triazol-4-yl)methyl)arylamide as a New Scaffold that Provides Rapid Access to Antimicrotubule Agents: Synthesis and Evaluation of Antiproliferative Activity Against Select Cancer Cell Lines [O] . Jonathan A. Stefely, Rahul Palchaudhuri, Patricia A. Miller, 2010

10. Dermal Sensitization Potential of Candidate Insect Repellents: LAIR Formulation (CHF1) N-(n-octyl) glutarimide (CHR2) N-(n-hexyl) glutarimide (CHR3) (E) 1,2,3,4-tetrahydro-6-methyl-1-(2-methyl-1-oxo-2-butenyl)quinoline (CHR5) 1,2,3,4-tetrahydro-6-methyl-1-(3-methyl-1-oxo-2-butenyl) quinoline (CHR6). [R] . Fruin, J. T., Hanes, M. A., Black, K., 1982

1. Natural compounds as anticancer agents: Experimental evidence [J] . Jiao Wang ,Yang-Fu Jiang . 世界实验医学杂志 . 2012,第3期

2. Phenolic Acids from iParthenium hysterophorus/i: Evaluation of Bioconversion Potential as Free Radical Scavengers and Anticancer Agents [J] . Richa Panwar ,Asvene Kumar Sharma ,Dharm Dutt . 生命科学与技术进展（英文） . 2015,第1期

3. Efficient Synthesis of a New Class of iN/i-Nucleosides of 4iH/i-Thiochromeno2,3-id/ipyrimidine-10-Sulfone as Potential Anticancer and Antibacterial Agents [J] . Abdulrahman G. Alshammari ,Abdel-Rhman B. A. El-Gazzar ,Hend N. Hafez . 有机化学国际期刊（英文） . 2013,第3期

4. 1-磷酰肼基-2-(1H-1,2,4-三唑-1-基)-4,4-二甲基-3-戊酮的合成及生物活性 [C] . 张耀谋 . 中国化工学会农药专业委员会第九届年会 . 1998

5. 3-(1H-1,2,4-三唑-1-基)亚甲基-4-(N-取代苯基)亚胺基-1,2,4-三唑-5-硫酮的合成及生物活性研究 [A] . 张彤彤 . 2014