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METHODS AND COMPOSITIONS USEFUL FOR DIAGNOSING INFLAMMATORY BOWEL DISEASE-ASSOCIATED NEOPLASIA

机译:诊断炎症性肠病相关性肝炎的方法和组合物

摘要

The present invention relates to the field of biomarkers. More specifically, the present invention relates to the use of microRNAs to diagnose and monitor various diseases such as cancer. In particular embodiments, microRNA expression levels can serve as diagnostic biomarkers in inflammatory bowel disease-associated neoplasia (IBDN). More specifically, in certain embodiments, the present invention can be used to differentiate or distinguish IBDN from sporadic colorectal cancer (S-CRC), IBD-Dysplasia, IBD and/or normal.
机译:本发明涉及生物标志物领域。更具体地,本发明涉及微小RNA在诊断和监测各种疾病例如癌症中的用途。在特定的实施方案中,微RNA表达水平可以用作炎症性肠病相关瘤形成(IBDN)中的诊断生物标志物。更具体地说,在某些实施方案中,本发明可用于区分IBDN与散发性结直肠癌(S-CRC),IBD-发育异常,IBD和/或正常。

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