USE OF SULPHATED GLYCOLIPIDS AS PROMOTERS OF NEURITIC GROWTH, MYELINATION AND INHIBITING THE PROLIFERATION OF ASTROGLIA AND MICROGLIA

摘要

A compound having formula I, in which R¹ is an alkenyl group C₅-C₂₅ containing one or more double carbon-carbon bonds, R² is selected independently from the group consisting of methyl and fluorinated methyl, and R³ and/or R⁴ is a SO₃M group, in which M is selected from the group consisting of hydrogen, alkali metal, ammonium and quaternary amine, the other being hydrogen or acyl is provided. The compound can be used for the production of a drug for the treatment of central nervous system disorders selected from the group consisting of lesions caused by CNS trauma, demyelinating diseases, neuro-inflammatory diseases and mental disorders caused a low level of BDNF.;