首页> 外国专利> METHOD FOR HARVESTING, PROCESSING, AND STORAGE OF PROTEINS FROM THE MAMMALIAN FETO-PLACENTAL UNIT AND USE OF SUCH PROTEINS IN COMPOSITIONS AND MEDICAL TREATMENT

METHOD FOR HARVESTING, PROCESSING, AND STORAGE OF PROTEINS FROM THE MAMMALIAN FETO-PLACENTAL UNIT AND USE OF SUCH PROTEINS IN COMPOSITIONS AND MEDICAL TREATMENT

机译:从哺乳动物的胎儿-妊娠中心单位收集,加工和存储蛋白质的方法以及在组合物和医学治疗中使用这种蛋白质的方法

摘要

The invention provides a method of harvesting, processing and storing a plurality of proteins from a mammalian feto-placental unit. The method includes dissecting a mammalian uterus to harvest at least one component of the mammalian feto-placental unit; blast freezing the component; and storing the blast frozen component; wherein the blast frozen component includes the proteins. In one embodiment, the method includes lyophilizing the blast frozen component to remove at least some water from the blast frozen component thereby creating a freeze-dried form; and storing the lyophilized component; wherein the lyophilized component includes the proteins. The invention also provides a composition including proteins from at least one lyophilized, blast frozen component of a harvested mammalian feto-placental unit reconstituted with a fluid. The invention further provides method of treatment of a disease or aging in a mammalian subject including administering to the mammalian subject a plurality of proteins from at least one blast frozen component harvested from a mammalian feto-placental unit; and reducing an accumulation of at least one intracellular protein in the subject.
机译:本发明提供了一种从哺乳动物胎盘单位中收获,加工和储存多种蛋白质的方法。该方法包括解剖哺乳动物子宫以收获哺乳动物胎儿-胎盘单元的至少一种成分;以及鼓风冻结组件;并储存爆炸后的冷冻成分;其中胚泡冷冻成分包括蛋白质。在一个实施方案中,该方法包括冻干急冻的组分以从急冻的组分中除去至少一些水,从而产生冻干的形式。并储存冻干成分;其中冻干组分包括蛋白质。本发明还提供了一种组合物,其包含来自至少一种用流体重建的哺乳动物胎盘单位的冻干,急冻冷冻成分的蛋白质。本发明进一步提供了一种在哺乳动物受试者中治疗疾病或衰老的方法,该方法包括给予该哺乳动物受试者多种蛋白质,这些蛋白质来自至少一种从哺乳动物胎盘单位收获的初生冷冻组分;和减少至少一种细胞内蛋白质在受试者中的积累。

著录项

  • 公开/公告号US2015079062A1

    专利类型

  • 公开/公告日2015-03-19

    原文格式PDF

  • 申请/专利权人 PATRICK J. CASEY;MURRAY HOARE;

    申请/专利号US201414551612

  • 发明设计人 MURRAY HOARE;PATRICK J. CASEY;

    申请日2014-11-24

  • 分类号A61K35/54;A61K38/17;A01N1/02;A61K35/50;

  • 国家 US

  • 入库时间 2022-08-21 15:25:16

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