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MEDICAMENT, METHOD, AND DRUG DELIVERY DEVICE FOR TREATMENT OF OVARIAN CANCER
MEDICAMENT, METHOD, AND DRUG DELIVERY DEVICE FOR TREATMENT OF OVARIAN CANCER
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机译:用于治疗卵巢癌的药物,方法和药物输送装置
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摘要
Drug delivery devices, medicaments, and methods are provided for the intraperitoneal treatment of ovarian cancer. An implantable device for drug delivery includes an elongated, flexible device having a housing defining a reservoir that contains a drug in solid or semi-solid form, and configured to be wholly deployed within the peritoneal cavity of a patient and continuously release a therapeutically effective amount of the drug over a period of at least 24 hours. A medicament includes cisplatin for administration into the peritoneal cavity of a patient continuously over a treatment period of at least 24 hours. A method of drug delivery includes implanting within the peritoneal cavity of a patient an elongated, flexible device having a reservoir containing a drug, solubilizing the drug at least in part with peritoneal fluid, and releasing an effective amount of the solubilized drug from the reservoir continuously for a period of at least 24 hours.
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