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CHARACTERIZATION OF CANCER USING DETECTION OF ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE (ALCAM) SHEDDING
CHARACTERIZATION OF CANCER USING DETECTION OF ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE (ALCAM) SHEDDING
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机译:利用活化的白细胞粘附分子(ALCAM)切皮法鉴定癌症
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摘要
The presently-disclosed subject matter includes labels for use in the identification of shed ALCAM in s sample from a subject. Further included are methods for characterizing, monitoring, evaluating treatment efficacy, or evaluating the progression of cancer in a subject that comprise providing a biological sample from the subject, determining the presence or amount of shed ALCAM in the biological sample, and then comparing the presence or the amount of the shed ALCAM to a reference. Differences between the presence or amount of shed ALCAM relative to the reference can be used to diagnose, prognosticate, treat, monitor, or otherwise characterize a cancer in a subject. Further provided are kits comprising a reagent and/or antibody for diagnosing, prognosticating, monitoring, or otherwise characterizing a cancer in a subject.
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