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Use of laquinimod for treating Crohn's disease patients who failed first-line anti-TNF therapy
Use of laquinimod for treating Crohn's disease patients who failed first-line anti-TNF therapy
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机译:拉喹莫德在治疗一线抗TNF治疗失败的克罗恩病患者中的用途
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摘要
This application provides for a method of treating a human patient afflicted with anti-TNFα refractory Crohn's disease, of treating a human patient afflicted with non-fibrostenotic Crohn's disease, and of treating a human patient whose Crohn's disease had not been surgically treated, the method comprising periodically administering to the patient an amount of laquinimod or pharmaceutically acceptable salt thereof effective to treat the patient. This application also provides for a method of inducing or maintaining clinical remission in a human patient afflicted with Crohn's disease comprising periodically administering to the patient an amount of laquinimod effective to induce or maintain clinical remission in the patient, which amount of laquinimod is less than 0.5 mg/day.
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