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Device and method for erythrocyte morphology analysis

机译:用于红细胞形态分析的装置和方法

摘要

The disclosure provides a device and a method for performing morphological analysis for erythrocytes, wherein the method for performing morphological analysis for erythrocytes comprises: collecting a morphological image of each of cells in a sample through a Charge Coupled Device (CCD) after amplifying the sample through an automatic microscope; segmenting and positioning the image and extracting target feature parameters after digitizing the image through an image-digital converter; isolating morphological feature parameters of each of the erythrocytes through a classifier established on the basis of the neural network, and normalizing each type of the morphological feature parameters of the erythrocytes through a feature fusion device established on the basis of fuzzy clustering; performing a statistical analysis on each type of normalized parameters obtained or performing a comprehensive statistical analysis according to a plurality of types of parameters, and expressing the result of the statistical analysis or the comprehensive statistical analysis in the form of graph or numerical table, thereby judging whether the morphology of the erythrocyte is normal. The source and property of the erythrocytes can be identified according to the detection for each type of the erythrocytes with the abnormal morphology.
机译:本公开提供了一种用于对红细胞进行形态分析的装置和方法,其中,用于对红细胞进行形态分析的方法包括:在将样品扩增通过后,通过电荷耦合器件(CCD)收集样品中每个细胞的形态图像。自动显微镜通过图像数字转换器对图像进行数字化之后,对图像进行分割和定位并提取目标特征参数;通过基于神经网络建立的分类器分离每个红细胞的形态特征参数,并通过基于模糊聚类建立的特征融合装置对红细胞的形态特征参数的每种类型进行归一化。对获得的每种归一化参数进行统计分析,或者根据多种参数进行综合统计分析,并以图形或数值表的形式表示统计分析或综合统计分析的结果,从而进行判断红细胞形态是否正常。可以根据对形态异常的每种类型的红细胞的检测来识别红细胞的来源和性质。

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