Coregistering images of needle biopsies using multiple weighted landmarks

摘要

A method for coregistering images involves defining middle paths through image objects depicting tissue slices of needle biopsies. First landmarks are defined on a first middle path through a first image object in a first digital image of a first tissue slice, and second landmarks are defined on a second middle path through a second image object of a second digital image of a second tissue slice. Individual first landmarks are associated with individual second landmarks. A first pixel in the first object is coregistered with a second pixel in the second object using multiple first and second landmarks. The first image is displayed in a first frame on a graphical user interface, and the second image is displayed in a second frame such that the first pixel is centered in the first frame, the second pixel is centered in the second frame, and the images have the same orientations.