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Bladder cancer diagnosis composition containing APE1/Ref-1 and bladder cancer diagnostic kit using same
Bladder cancer diagnosis composition containing APE1/Ref-1 and bladder cancer diagnostic kit using same
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机译:含有APE1 / Ref-1的膀胱癌诊断组合物和使用该组合物的膀胱癌诊断试剂盒
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摘要
Provided are a bladder cancer diagnosis composition containing APE1/Ref-1, a bladder cancer diagnostic kit containing an antibody which specifically binds to the APE1/Ref-1, and a method of measuring APE1/Ref-1 concentration in biological samples through an antigen-antibody binding reaction using the antibody which specifically binds to the APE1/Ref-1. According to the invention, the APE1/Ref-1 protein concentration in serum of bladder cancer patients is significantly higher than in healthy subjects, and more particularly, it significantly increases in the serum of patients with stage 2 or later bladder cancer.
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