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composition of ethanolic extract and dichloromethane fraction rich in naphthoquinones and use as antimalarial agent

机译:富含萘醌的乙醇提取物和二氯甲烷馏分的组成并用作抗疟药

摘要

composition of ethanolic extract and dichloromethane fraction rich in naphthoquinones and use as antimalarial agent. The present invention describes the process for obtaining the dichloromethane fraction and subfractions of eleutherine plicata, commonly referred to as "marupazinho, marupari, hover, coconut, marupai, marupaú, marupá-piranga, irium-washa-paimaira". The invention further comprises describing the method of obtaining this fraction and its composition as well as identifying a naphthoquinone. this fraction was tested and showed antiplasmodic activity, particularly against chloroquine resistant (w2) plasmodium falciparum.
机译:乙醇提取物和富含萘醌的二氯甲烷馏分组成,并用作抗疟药。本发明描述了获得依色林的二氯甲烷级分和亚级分的方法,通常称为“ marupazinho,marupari,hover,椰子,marupai,marupaú,marupá-piranga,irium-washa-paimaira”。本发明进一步包括描述获得该级分及其组成以及鉴定萘醌的方法。测试了该级分,并显示出抗疟原虫活性,尤其是对氯喹抗药性(w2)恶性疟原虫。

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