首页> 外国专利> THERAPEUTIC AGENT FOR TREATMENT OF LIVER DISEASES CONTAINING 2-AMINE-1, 3-PROPANEDIOL DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR TREATMENT OF LIVER DISEASES

THERAPEUTIC AGENT FOR TREATMENT OF LIVER DISEASES CONTAINING 2-AMINE-1, 3-PROPANEDIOL DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR TREATMENT OF LIVER DISEASES

机译:治疗以2-胺-1、3-丙二醇衍生物为活性成分的肝病治疗剂和治疗肝病的方法

摘要

A novel therapeutic agent for organ disease, in particular, a therapeutic agent for liver disease is provided. It has been found that a diarylsulfide or diarylether derivative having 2-amino-1,3-propanediol structure, the compound that act as a sphingosine-1-phosphate receptor agonist, and a pharmaceutically acceptable salt and hydrate thereof are used as effective therapeutic agents for various diseases in organs, in particular liver diseases. The diarylsulfide or diarylether derivative is represented by the following general formula (1):
机译:提供了一种用于器官疾病的新型治疗剂,特别是一种用于肝病的治疗剂。已经发现具有2-氨基-1,3-丙二醇结构的二芳基硫醚或二芳基醚衍生物,作为鞘氨醇-1-磷酸受体激动剂的化合物及其药学上可接受的盐和水合物被用作有效的治疗剂。用于器官的各种疾病,特别是肝脏疾病。二芳基硫醚或二芳基醚衍生物由以下通式(1)表示:

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