Flaviviridae family mutant virus, pharmaceutical composition, nucleic acid, mutated virus capsid protein, method for producing a modified virus and method for producing a modified nucleic acid

摘要

The present invention relates to a mutant virus of the family flaviviridae, comprising a deletion in the capsid protein of at least 20 successive amino acids, without any further deletion, substitution or insertion mutation except of the amino acids next to the deletion, which may be substituted.