Pharmaceutical composition comprising Dimethyl fumarate; Preparation method; microtabletas Capsule comprising Dimethyl fumarate; method for the treatment, prevention or Improvement of Multiple sclerosis.

摘要

Provided herein are compositions containing compounds, or pharmaceutically acceptable salts, that metabolize to monomethyl fumarate with certain pharmacokinetic parameters and methods for treating, prophylaxis, or amelioration of neurodegenerative diseases including multiple sclerosis using such compositions in a subject, wherein if the compositions contain dimethyl fumarate, the total amount of dimethyl fumarate in the compositions ranges from about 43% w/w to about 95% w/w.