Union Molecule that binds specifically to inteleuquina 6 (IL - 6); Pharmaceutical composition that comprises; Nucleic Acid; vector; host Cell; and use for treating disease or Disorder associated with il-6.

摘要

The present invention provides binding molecules (e.g., antibodies or antigen binding fragments thereof) that specifically bind to and inhibit the biological activity of IL-6 (e.g., human, mouse and non-human primate IL-6). In a preferred embodiment, the antibodies or antigen binding fragments of the invention bind to IL-6 and inhibit its binding to an IL-6 receptor. Such antibodies or antigen binding fragments are particularly useful for treating IL-6-associated diseases or disorders (e.g., inflammatory disease and cancer).