首页> 外国专利> Composition for modulating the expression of genes responsible for the function and maintenance of keratinous materials comprising Lipid Carrier and a Pharmaceutical Plant and / or cosmetically acceptable; Cosmetic or therapeutic methods for treating keratinous Materials, which includes Administration of the composition to a subject.

Composition for modulating the expression of genes responsible for the function and maintenance of keratinous materials comprising Lipid Carrier and a Pharmaceutical Plant and / or cosmetically acceptable; Cosmetic or therapeutic methods for treating keratinous Materials, which includes Administration of the composition to a subject.

机译:用于调节负责角蛋白材料的功能和维持的基因表达的组合物,包括脂质载体和药用植物,和/或化妆品可接受的;用于治疗角蛋白材料的美容或治疗方法,包括将组合物施用于受试者。

摘要

The present invention is directed to cosmetic and/or pharmaceutical compositions comprising at least one plant lipid, having as its main application the treatment of keratinous materials, particularly skin, hair, scalp, nails and eyelashes, by modulating the expression of genes responsible for ROS metabolism, lipid metabolism, skin integrity, cell renewal, cell differentiation, strengthening the skin barrier, calcium metabolism, cell proliferation, tissue healing and/or repair, cell adhesion, carbohydrate metabolism, hydration, skin homeostasis/maintenance, skin defense and/or protection, remodeling and/or extracellular matrix synthesis, skin peeling, tissue maintenance, cell signaling, normal development of the epidermis, epidermal barrier function, development of the skin, dermis-epidermis junction, anti-inflammatory or antioxidant action in keratinous materials, through the modulation of the expression of the genes involved in said functions. The present invention also teaches methods of modulating the expression of genes responsible for such functions of keratinous materials and the use of said plant lipids in the preparation of said compositions.
机译:本发明涉及包含至少一种植物脂质的化妆品和/或药物组合物,其主要应用是通过调节负责ROS的基因的表达来治疗角蛋白,特别是皮肤,头发,头皮,指甲和睫毛。代谢,脂质代谢,皮肤完整性,细胞更新,细胞分化,增强皮肤屏障,钙代谢,细胞增殖,组织愈合和/或修复,细胞粘附,碳水化合物代谢,水合作用,皮肤稳态/维持,皮肤防御和/或保护,重塑和/或细胞外基质合成,皮肤剥离,组织维持,细胞信号传导,表皮的正常发育,表皮屏障功能,皮肤的发育,真皮-表皮连接,角质材料中的抗炎或抗氧化作用调节涉及所述功能的基因的表达。本发明还教导了调节负责角蛋白物质的这种功能的基因的表达的方法,以及所述植物脂质在制备所述组合物中的用途。

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