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Serum cholesterol lowering agent or preventative or therapeutic agent for the treatment of atherosclerosis.

机译:血清胆固醇降低剂或预防或治疗剂,用于治疗动脉粥样硬化。

摘要

A serum cholesterol lowing agent or a preventive or therapeutile agent for atherosclerosis, which each comprises a combination of a compound represented by the following general formula (I) or pharmaceutical acceptable salts thereof with a cholesterol biosynthesis inhibitor and/or a fibrate type cholesterol lowing agent. (I) (b) (a) [In the formula, A 1 , A 2 , A 3 and A 4 each is hydrogen, a group represented by the formula (b), or a group represented by the formula (a), provided that at least one of these is a group represented by the formula (a); A 2 is C 1-5 alkyl etc; and n. p, q and r each is an integer of 0, 1 or 2.
机译:血清胆固醇降低剂或动脉粥样硬化的预防或治疗剂,其各自包含以下通式(I)表示的化合物或其药学上可接受的盐与胆固醇生物合成抑制剂和/或贝特类的胆固醇降低剂的组合。 (I)(b)(a)[式中,A 1,A 2,A 3和A 4分别为氢,式(b)表示的基团或式(a)表示的基团,前提是这些中的至少一个是由式(a)表示的基团; A 2为C 1-5烷基等;和p,q和r均为0、1或2的整数。

著录项

  • 公开/公告号DK1655037T3

    专利类型

  • 公开/公告日2015-08-24

    原文格式PDF

  • 申请/专利权人 KOTOBUKI PHARMACEUTICAL CO. LTD.;

    申请/专利号DK20040746153T

  • 申请日2004-06-15

  • 分类号A61P3/06;A61K31/216;A61K31/397;A61K31/40;A61K31/505;A61K31/7052;A61K45;A61K45/06;A61P9/10;A61P43;C07D405/10;C07D405/12;

  • 国家 DK

  • 入库时间 2022-08-21 15:15:44

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