Diazen-1-ium-1,2-diolate compounds, compositions comprising same and uses of such compounds and compositions for inhibiting biofilm formation and regulating dispersal of microorganisms from biofilms

摘要

The present invention relates generally to methods and compounds for regulating the release of nitric oxide in the vicinity of biofilm-forming microorganisms to regulate programmed cell death in the microorganisms and thereby promote dispersal of microorganism from biofilms and/or inhibit biofilm formation or development. More particularly, the invention relates to the use of compounds to provide spatial and temporal control over nitric oxide release.