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Hepatoprotective drug by using cichorium intybus extract in novel polysaccharide

机译:菊苣提取物在新型多糖中的保肝作用

摘要

The present invention provides a novel hepatoprotective drug by using Cichorium intybus extract in novel polysaccharide i.e. partially hydrolyzed tora gum (PHTG) which leads to enhanced absorption and sustained release of the drug. PHTG not only increases the drug absorption but also reduces scarring of the liver, thus preventing liver damage. The formulation is tested for its effectiveness against DEN (Diethylnitrosamine) induced toxicity in male wistar rats and has exhibited a very promising protective role.
机译:本发明通过在新多糖即部分水解的托拉胶(PHTG)中使用菊苣菊(Cichorium intybus)提取物来提供一种新型的肝保护药物,这导致药物的吸收和持续释放。 PHTG不仅增加了药物吸收,还减少了肝脏的瘢痕形成,从而防止了肝损害。测试了该制剂对DEN(二乙基亚硝胺)诱导的雄性wistar大鼠毒性的有效性,并显示出非常有前途的保护作用。

著录项

  • 公开/公告号IN2013DE02831A

    专利类型

  • 公开/公告日2015-10-02

    原文格式PDF

  • 申请/专利权人 UNIV AMITY;

    申请/专利号IN2013DEL2831

  • 申请日2013-09-25

  • 分类号A61K;

  • 国家 IN

  • 入库时间 2022-08-21 15:14:16

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