Gel based drug delivery system comprising self emulsifying formulation

摘要

GEL BASED DRUG DELIVERY SYSTEM COMPRISING SELF EMULSIFYING FORMULATION The present invention involves development of a drug delivery system comprising a matrix entrapping the pharmaceutically active ingredient dissolved in self emulsifying formulation for improved delivery of wide variety of pharmaceutical active ingredients for oral delivery. The drug delivery system is a gel composition including the gel forming matrix, self emulsifying oil formulation, cross-linking agent. The self emulsifying formulation contains different combination of lipophilic active pharmaceutical ingredient, hydrophilic surfactant, lipophilic surfactant and triglycerides. The composition of present invention can be used for improved delivery and remove instability of oil formulation with soft and hard gelatin capsule thus can increase the durability and stability of the formulation.