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Method for mini-invasive treatment of massive hepatic metastases

机译:微创治疗大面积肝转移的方法

摘要

The invention relates to medicine, particularly to hepatology and oncology, and can be used for mini-invasive treatment of massive hepatic metastases in patients with liver cirrhosis.According to the invention, the claimed method consists in that through the laparoscopic access in the infraumbilical region under video optics control is introduced an additional trocar in the subhepatic region, is removed the ascitic fluid from the abdominal cavity, is identified the hepatic tumor focus and is performed the biopsy sampling from the tumor, then using a bipolar electrode, which is introduced through the trocar port, is performed the bipolar diathermocoagulation with the frequency of 300 kHz and the power of 100…250 W of the tumor central surface with the slow movement of the electrode in its depths with the continued thermodestruction of tumor tissue without damaging the adjacent hepatic tissue, for 3…7 minutes in pulsating regimen, at the same time on the periphery of the intact hepatic tissue is infiltrated 15…30 ml of a mixture comprising per 1 ml:then in the same points is infiltrated fibrinogen sol. 15…30 mg, afterwards in the subhepatic space is introduced a checking drain for 2…5 days and is performed the peritoneal lavage with a mixture containing broad spectrum antibiotics and proteolytic enzymes.
机译:本发明涉及药物,特别是涉及肝癌和肿瘤学,并且可以用于肝硬化患者的大规模肝转移的微创治疗。根据本发明,所要求保护的方法在于通过腹腔镜进入脐下区域在视频光学控制下,在肝下区域引入另外的套管针,从腹腔中去除腹水,确定肝肿瘤灶,并从肿瘤进行活检,然后使用双极电极,通过套管针端口进行双极高频透热凝结,频率为300 kHz,肿瘤中心表面的功率为100…250 W,电极在其深度中缓慢移动,同时肿瘤组织持续热破坏,而不会损害相邻的肝组织,在脉动方案中持续3…7分钟,同时在完整肝组织周围问题是渗透到15…30 ml每1 ml的混合物中:然后在同一点渗入纤维蛋白原溶胶。 15…30 mg,然后在肝下间隙引入排泄液,持续2…5天,并用含有广谱抗生素和蛋白水解酶的混合物进行腹膜灌洗。

著录项

  • 公开/公告号MD880Z

    专利类型

  • 公开/公告日2015-09-30

    原文格式PDF

  • 申请/专利权人 ANGHELICI GHEORGHE;

    申请/专利号MDS20140074

  • 发明设计人 ANGHELICI GHEORGHE;

    申请日2014-05-21

  • 分类号A61B18/12;A61B18/14;A61K33/06;A61K38/36;A61K38/43;

  • 国家 MD

  • 入库时间 2022-08-21 15:14:01

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