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New ((4-substituted) thiazol-2-yl) hydrazonomethyl-N,N-bis(2-chloroethyl) anilines and method for producing them

机译:新的((4-取代的)噻唑-2-基)肼基甲基-N,N-双(2-氯乙基)苯胺及其制备方法

摘要

new ((4 - substituted) thiazole - 2 - yl) hydrazonametylo - n, n '- bis (2-chloroethyl) - aniline (1 - 8) of the formula 1 in which r = br, no2, cn, f, nhso2ch3, model 2, model 3 and model 4 and method of production new ((4 - substituted) thiazole - 2 - yl) hydrazonametylo - n, n' - bis (2-chloroethyl) anilin (1 - 8) is n and treatment of n, n-bis (2-chloroethyl) aminobenzaldehyd (10).tiosemikarbazydem (11) catalysed reaction with concentrated sulphuric acid in a mixture of organic solvent and water, boiling to obtain tiosemikarbazonu (9),and then cyklizacji in inert environment obtained tiosemikarbazonu (9) with the corresponding 2 - chloro - or bromo - 2 - 1 - fenyloetanonami in anhydrous organic solvent and products yields a way.
机译:式1的新的((4-取代的)噻唑-2-基)肼基噻吩基-n,n'-双(2-氯乙基)-苯胺(1-8),其中r = br,no2,cn,f,nhso2ch3 ,模型2,模型3和模型4以及新的((4-取代)噻唑-2-基)肼基噻吩基-n,n'-双(2-氯乙基)苯胺(1-8)的生产方法n,n-双(2-氯乙基)氨基苯甲醛(10).tiosemikarbazydem(11)与浓硫酸在有机溶剂和水的混合物中催化反应,沸腾得到tiosemikarbazonu(9),然后在惰性环境下cyklizacji得到tiosemikarbazonunu (9)用相应的2-氯-或溴-2--1-芬太子酮在无水有机溶剂中制得产物。

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