Improved synthesis of a biosynthetic product with an arranged composition of biosynthetic enzymes on a Nukleotidsequenzmotiv

摘要

The invention relates to a method for synthesizing a compound using biosynthetic routes with the cultivation of genetically modified host cells, wherein the cells are changed with one or more nucleic acids, wherein the nucleic acid contain the nucleotide sequences of chimeric proteins of enzymes of the biosynthetic path or other functional polypeptides and factors, which bind to nucleic acid, are composed, and the program-nucleic acid sequence containing the target for nucleic acid, which are recognized by the above factors of the chimeric protein, which bind to the factors on the nucleic acid and the said program-Nukleotisequenz for arrangement of the enzymes of the biosynthetic pathway, or other functional polypeptides along the program nucleic acid sequence is used and said cultivation for the synthesis of said chimeric proteins in genetically modified host cells is used, resulting in the production of said compound. The invention relates to host cells with the nucleic acid sequence program, with the nucleic acid sequence expressing the chimeric proteins. The invention describes methods to better synthesis of the compound.