Method for obtaining fibroin particles regenerated using ionic liquids and ultrasound

摘要

Method for obtaining particles fibroin regenerated using ionic and ultrasonic liquid. # The present invention relates to a process for the dissolution of insoluble fibrous proteins, or sparingly soluble in water (i.e. fibroin) comprising mixing said protein with a liquid ion molten temperature below 100 ° C and applying pulses of high power ultrasound to the mixture until complete dissolution. A procedure is contemplated for protein particles (fibroin) regenerated from the homogeneous protein solution ionic liquid obtained by the above process which comprises cooling the solution to a temperature between 30 and 65 ° C, the dispersion of the solution in a precipitant solvent maintained under stirring, separation of protein particles regenerated in solid form of the solution of the precipitant solvent, and washing and drying of the particles. Finally, the present invention relates to regenerated fibroin particles obtained by said process.