Device for the detection of a single molecule in situation of nanoconfination and in dynamic regime, procedure of manufacture and use (Machine-translation by Google Translate, not legally binding)

摘要

Device for the detection of a single molecule in a nanoconfining situation and in a dynamic regime, manufacturing and use procedure. The object of the present invention is related to a device that integrates photonic crystal structures and micro-nanochannels for the manipulation and detection of dna molecules and other molecules with luminescent markers. The device, based on the ability of the photonic guides to direct the electromagnetic waves, concentrates the emission signal of the molecule in response to an excitation signal in a given direction. Objects of the present invention are also the method of manufacturing the device and the use thereof for the detection of a single molecule in a nanoconfiguration situation and in a dynamic regime. (Machine-translation by Google Translate, not legally binding)