genetic signature of CD4 + T cells in rheumatoid arthritis (RA)

摘要

A method for diagnosing rheumatoid arthritis in a patient, the method comprising: obtaining a sample of CD4 + T cells from the patient; and determining the expression levels of all genes of the group consisting of SOCS3 BCL3 PIM1 SBNO2 LDHA CMAH NOG PDCD1 IGFL2 LOC731186 GPRIN3 MUC1; and comparing said expression levels with reference expression levels, wherein a difference in the expression of said genes indicates an increased likelihood of the patient having rheumatoid arthritis (RA)