USE OF PARASITIC BIOLOGICAL AGENTS FOR PREVENTION AND CONTROL OF AUTOIMMUNE DISEASES

摘要

The invention relates to a method of treating an excessive immune responseincluding an aberrant/enhanced Th1 response by administering a helminthicparasite preparation in an amount sufficient to reduce the excessive immuneresponse in an individual. This invention is generally directed to autoimmunediseases which involve an excessive immune response or an aberrant/enhancedTh1 response. More specifically, the present invention is directed to thetreatment of Crohn's disease and ulcerative colitis, both known as IBD. Whilethe present invention discloses specific information about the treatment ofIBD, the disclosure is in no way limiting. Additionally, rheumatoid arthritis,type 1 diabetes mellitus, lupus erythematosis, sarcoidosis and multiplesclerosis can be treated by the methods and compositions disclosed therein.