The present invention provides a safe and effective vaccine compositionagainstWest Nile virus disease. An immunogenically active component of West Nilevirus,an adjuvant such as a metabolizable oil, and a pharmacologically acceptablecarrierare formulated into an immunizing vaccine. The invention also provides amethodfor the prevention or amelioration of West Nile disease, such as encephalitis,inequidae by administering the vaccine composition herein set forth.
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