Use of the association of a sinus node If current inhibitor and an angiotensin-converting enzyme inhibitor in the treatment of heart failure

摘要

#$%^&*AU2011202607B220150212.pdf#####USE OF THE ASSOCIATION OF A SINUS NODE IF CURRENT INHIBITOR AND AN ANGIOTENSIN-CONVERTING ENZYME INHIBITOR IN THE TREATMENT OF HEART FAILURE Abstract The invention relates to the use of the association of a selective and specific sinus node Ir current inhibitor, more especially ivabradine or N-{[(7S)-3,4dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}-3-(7,8-dimethoxy-1,2,4,5tetrahydro-3H-3-benzazepin-3-yl)-N-methyl-3-oxo-1-propanamine, and an agent that 5 inhibits angiotensin-converting enzyme, in obtaining medicaments intended for the treatment of heart failure, more especially heart failure having preserved systolic function. Medicaments are also disclosed.