首页> 外国专利> COMPOSITION FOR PREVENTING OR TREATING FATTY LIVER COMPRISING EVODIAE FRUCTUS EXTRACT AND ALKALOID COMPOUND ISOLATED THEREFROM AS ACTIVE INGREDIENTS

COMPOSITION FOR PREVENTING OR TREATING FATTY LIVER COMPRISING EVODIAE FRUCTUS EXTRACT AND ALKALOID COMPOUND ISOLATED THEREFROM AS ACTIVE INGREDIENTS

机译:预防或治疗由吴茱F提取物和经碱复方分离得到的碱类化合物作为有效成分的脂肪肝的组合物

摘要

The present invention relates to a composition for preventing or treating fatty liver, the composition comprising Evodiae fructus extract and an alkaloid compound isolated therefrom as active ingredients. The Evodiae fructus extract and alkaloid compound isolated therefrom of the present invention are stable inside the body, increase the activity of ANT1 enzyme, and promote lipid oxidation in liver tissue in a fatty-liver animal model and thereby effectively suppress lipid accumulation and triglyceride production, and thus can be used to advantage in the prevention or treatment of fatty liver and in particular non-alcoholic fatty liver.
机译:本发明涉及一种用于预防或治疗脂肪肝的组合物,该组合物包含吴茱E提取物和从中分离出的生物碱化合物作为活性成分。从中分离出的本发明的<吴>叶提取物和生物碱化合物在体内是稳定的,增加了ANT1酶的活性,并促进了脂肪肝动物模型肝组织中的脂质氧化,从而有效地抑制脂质积累和甘油三酸酯的产生,因此可以有利地用于预防或治疗脂肪肝,尤其是非酒精性脂肪肝。

著录项

  • 公开/公告号WO2014208799A1

    专利类型

  • 公开/公告日2014-12-31

    原文格式PDF

  • 申请/专利权人 THE ASAN FOUNDATION;

    申请/专利号WO2013KR05748

  • 发明设计人 LEE KI UP;OH WON KEUN;KOH EUN HEE;

    申请日2013-06-28

  • 分类号A61K36/754;A61K31/122;A61P1/16;

  • 国家 WO

  • 入库时间 2022-08-21 15:09:13

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