Anti-Dual Endothelin-1/Angiotensin II receptor (DEAR) antibody for inhibiting disease-associated or pathological angiogenesis.

摘要

The present application is directed to the identification of mutations and/or polymorphisms in the Dual Endothelin-1/Angiotensin II Receptor (Dear) that indicate susceptibility to, or show current affliction with, hypertension. Additionally, the present invention discloses methods for the modulation of angiogcncsis via the regulation of Dear.