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BIOLOGICAL DEVICES AND METHODS OF USE THEREOF FOR THE STUDY AND CONTROL OF ALZHEIMER'S DISEASE

机译:研究和控制阿兹海默氏病的生物装置及其使用方法

摘要

Described herein are devices and methods for simultaneously expressing amyloid precursor protein and TonB protein. For example, the biological devices and methods described herein increase the production of these two proteins while also reducing the cost, making these proteins more widely accessible for medical research purposes, including for the development of diagnostic tests for Alzheimer's disease. The amyloid precursor protein and TonB protein produced by the devices and methods described herein, as well as the devices themselves, can be used in experiments designed to model the interactions between metals and β-amyloid that are characteristic of Alzheimer's disease.
机译:本文描述了同时表达淀粉样蛋白前体蛋白和TonB蛋白的装置和方法。例如,本文描述的生物装置和方法增加了这两种蛋白质的产生,同时还降低了成本,使得这些蛋白质更广泛地可用于医学研究目的,包括用于阿尔茨海默氏病诊断测试的开发。通过本文所述的装置和方法产生的淀粉样蛋白前体蛋白和TonB蛋白,以及装置本身,可用于设计用于模拟金属和β-淀粉样蛋白之间相互作用的实验中,所述相互作用是阿尔茨海默氏病的特征。

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