首页> 外国专利> METHODS FOR DETERMINING THE SUSCEPTIBILITY OF A SUBJECT TO CONTRACT A NOSOCOMIAL INFECTION AND FOR ESTABLISHING A PROGNOSE OF EVOLUTION OF SEPTIC SYNDROME

METHODS FOR DETERMINING THE SUSCEPTIBILITY OF A SUBJECT TO CONTRACT A NOSOCOMIAL INFECTION AND FOR ESTABLISHING A PROGNOSE OF EVOLUTION OF SEPTIC SYNDROME

机译:确定受试者感染医院感染的敏感性和建立癫痫综合征演变的方法

摘要

The present invention relates to a method for determining the likelihood of a patient contracting a nosocomial infection and to a method for determining the prognosis of the course of a septic syndrome in a patient, according to which: a. a biological sample is obtained from the patient and biological material is extracted from the biological sample; b. at least one specific reagent is obtained from an expression construct of at least one target gene selected from target genes S100A9 and S100A8; c. the expression of at least one of the target genes S100A9 and S100A8 is determined, an overexpression relative to a predetermined threshold value indicating the likelihood of contracting a nosocomial infection as well as indicating a poor prognosis of the course of a septic syndrome.
机译:本发明涉及一种确定患者患上医院感染的可能性的方法,以及一种确定患者败血症综合症病程的预后的方法,根据该方法:从患者获得生物样品,并从生物样品中提取生物材料; b。从至少一种选自靶基因S100A9和S100A8的靶基因的表达构建体获得至少一种特异性试剂; C。确定靶基因S100A9和S100A8中至少一个的表达,相对于预定阈值的过表达指示发生医院感染的可能性以及败血综合症病程的预后不良。

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