MAGNETIZATION TRANSFER CONTRAST TECHNIQUE FOR CHEMICAL EXCHANGE SATURATION TRANSFER (CEST) MRI BY LOCALIZED STEAM AND METHOD OF OPERATION THEREOF

摘要

A magnetic resonance imaging (MRI) system (600),for acquiring magnetic resonance (MR) information of a volume, includes at least one controller (610) configured generate at least a portion of a stimulated echo acquisition mode (STEAM) CESTsequence including first through third 90º radio frequency (RF) pulses, and a first pulse train situated before the first 90º RF pulse. The first pulse train has first number of pulses. The controller (610) is further configured to generate at least another portion of the STEAM CEST sequence comprising a second pulse train situated between the second and third 90º RF pulses, the second pulse train comprising a second number of pulses which is less than the first number of pulses;generating end of spoil gradients;and/or to acquire MR information during an acquisition window which is stated at least partially after the end of spoil gradients.