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IL-6 DETECTION BASED EARLY DIAGNOSIS AND PREDICTION OF SYSTEMIC INFLAMMATORY RESPONSE SYNDROME AND SEPSIS IN ASYMPTOMATIC PATIENTS
IL-6 DETECTION BASED EARLY DIAGNOSIS AND PREDICTION OF SYSTEMIC INFLAMMATORY RESPONSE SYNDROME AND SEPSIS IN ASYMPTOMATIC PATIENTS
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机译:IL-6检测在无症状患者中的早期诊断和系统性炎症反应综合征和脓毒症的预测
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摘要
Methods, systems and kits for the early diagnosis or prediction of systemic inflammatory response syndrome (SIRS) including sepsis in asymptomatic patients, such as patients undergoing a surgical intervention, are provided. Some embodiments include a method and system for the detection or diagnosis of SIRS, or detection or diagnosis of a risk to suffer from or develop SIRS, in an asymptomatic patient comprising the steps of determining the level of IL-6 (or a variant thereof) in a sample from the patient; comparing the level of IL-6 (or a variant thereof) to a reference level; detecting or diagnosing SIRS or diagnosing a risk to suffer from or develop SIRS, wherein the sample is isolated at least 2 times at short intervals and the determining and comparing steps are both repeated for each sample. Also provided are methods, systems and kits for therapy monitoring and mortality prediction.
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