METHODS FOR IDENTIFYING COMPOUNDS WHICH MODULATE INTERLEUKINS 17 AND 23 SIGNALING ACTIVITY

摘要

Provided are antisense oligonucleotides and other agents that target and modulate IL-17 and/or IL-23 signaling activity in a cell, compositions that comprise the same, and methods of use thereof. Also provided are animal models for identifying agents that modulate 17 and/or IL-23 signaling activity.