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Dichlorido complexes of platinum with 7-azaindole halogeno-derivatives for use in the treatment of tumour diseases

机译:铂与7-氮杂吲哚卤代衍生物的二氯基配合物,用于治疗肿瘤疾病

摘要

The utilization of dichlorido complexes of platinum in the oxidation state +II and their crystal-solvates having the structural formula (I), where at least one of the hydrogen atoms localized on the carbon atoms C3, C4 or C5 of the 7-azaindole skeleton is substituents by at least one atom from the group of: chlorine, bromine, or iodine, for the preparation of drugs for the treatment of ovarian carcinoma and/or prostate carcinoma and/or lung carcinoma and/or cervix carcinoma and/or malignant melanoma.
机译:氧化态+ II的铂的二氯基络合物及其具有结构式(I)的晶体溶剂化物的利用,其中位于7-氮杂吲哚骨架的碳原子C3,C4或C5上的氢原子中的至少一个是被氯,溴或碘中的至少一个取代的取代基,用于制备用于卵巢癌和/或前列腺癌和/或肺癌和/或子宫颈癌和/或恶性黑色素瘤的治疗。

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