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SULFATED AND UNSULFATED FLAVONOID OLIGOMERS AS CANCER THERAPEUTICS

机译：硫酸盐类和非硫酸盐类寡聚体作为癌症的治疗方法

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摘要

Sulfated and unsulfated flavonoid oligomers as inhibitors of cancer stem cells (CSCs) are provided. In particular, sulfated flavonoid dimers are shown to selectively inhibit CSCs growth and self-renewal both in vitro and in vivo.

机译：提供了作为癌症干细胞（CSCs）抑制剂的硫酸化和未硫酸化的类黄酮低聚物。特别是，硫酸化的类黄酮二聚体显示出选择性地抑制CSCs的生长和在体外和在体内自我更新。 展开▼

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公开/公告号WO2015069979A2

专利类型

公开/公告日2015-05-14

原文格式PDF

申请/专利权人 VIRGINIA COMMONWEALTH UNIVERSITY;
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申请/专利号WO2014US64481

发明设计人 DESAI UMESH R.;KARUTURI RAJESH;PATEL BHAUMIK B.;PATEL NIRMITA J.;
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申请日2014-11-07

分类号C07D407/12;C07D407/10;A61K31/352;A61K31/35;A61P35;

国家 WO

入库时间 2022-08-21 15:06:38

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