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G-PROTEIN COUPLED RECEPTOR FUSION EXPRESSING PROTEIN

机译:G蛋白偶联受体融合表达蛋白

摘要

The present invention relates to a G-protein coupled receptor fusion expressing protein, which is derived from eukaryotes. The G-protein coupled receptor fusion expressing protein is selected from a APC protein fragment or proteins having a homology of greater than 90% to the sequence of said fragment; or an RGS16 protein fragment or proteins having a homology of greater than 90% to the sequence of said fragment; a DNJ protein fragment or proteins having a homology of greater than 90% to the sequence of said fragment. For the G-protein coupled receptor fusion expressing protein of the present invention, such fusion expressing proteins and G-protein coupled receptors are fused and expressed, so as to increase the expression yield and the in vitro stability of G-protein coupled receptors. The G-protein coupled receptor fusion expressing protein of the present invention is widely applicable to studies on G-protein coupled receptors.
机译:G蛋白偶联受体融合表达蛋白技术领域本发明涉及G蛋白偶联受体融合表达蛋白,其衍生自真核生物。 G蛋白偶联受体融合表达蛋白选自APC蛋白片段或与所述片段序列具有大于90%同源性的蛋白。 RGS16蛋白质片段或与所述片段的序列具有大于90%的同源性的蛋白质;或DNJ蛋白质片段或与所述片段的序列具有大于90%的同源性的蛋白质。对于本发明的G蛋白偶联受体融合表达蛋白,将这种融合表达蛋白与G蛋白偶联受体融合并表达,以增加G蛋白偶联受体的表达产量和体外稳定性。本发明的G蛋白偶联受体融合表达蛋白可广泛用于G蛋白偶联受体的研究。

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