CONTINUOUS AND REAL-TIME CALIBRATION OF FIBER-BASED MICROSCOPIC IMAGES

摘要

A method for processing images acquired by image detectors with non-uniform transfer functions and irregular spatial locations includes the steps of accumulating data from multiple images, defining an affinity graph which edges define pairs of detectors that measure related signal, performing statistical analysis on the accumulated data with respect to each pair of detectors, and solving a system of equations constructed from the results of the statistical analysis to estimate each detector transfer function, a set of solutions to the system of equations comprising a calibration of an imaging system.