RECRYSTALLISED DEHYDRATED ENROFLOXACIN HYDROCHLORIDE COMPLEX, AND METHOD FOR PRODUCING SAME

摘要

The invention relates to a recrystallised dehydrated enrofloxacin hydrochloride complex of formula (I) wherein the acid recrystallisation and formation of complexes with chloride, magnesium and sulfate produce a highly-soluble recrystallised enrofloxacin hydrochloride which provides, subcutaneously, maximum serum concentrations (Cmax) and areas under the curve (AUC) of concentration vs. time larger than those achieved with the basic enrofloxacin.