首页>
外国专利>
CANCER TREATMENTS USING ERK1/2 AND BCL-2 FAMILY INHIBITORS
CANCER TREATMENTS USING ERK1/2 AND BCL-2 FAMILY INHIBITORS
展开▼
机译:使用ERK1 / 2和BCL-2家族抑制剂的癌症治疗
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention provides, inter alia, methods for treating or ameliorating the effects of a cancer in a subject in need thereof. These methods include administering to the subject an effective amount of (i) an ERK1/2 inhibitor (such as BVD-523) or a pharmaceutically acceptable salt thereof and (ii) a BCL-2 family inhibitor (such as navitoclax) or a pharmaceutically acceptable salt thereof, to treat or ameliorate the effects of the cancer. Kits and pharmaceutical compositions for treating or ameliorating the effects of a cancer in a subject and methods for selecting a subject with cancer that may benefit from a combination drug therapy are also provided.
展开▼