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SUBMUCOSAL CUSHIONING AGENT

机译:胃底缓冲剂

摘要

In order to improve the resection efficiency, operability, and safety of endoscopic mucosal resection operations, a method has conventionally been employed wherein a cushion agent such as physiological saline is injected into the layer below the area designated for resection, causing the lesion to lift and protrude (hereafter simply referred to as "protrusion"), after which the lesion is removed. It is difficult to accurately remove the intended area using conventional cushion agents because applying pressure to the protrusion tends to cause deformation thereof, the degree of protrusion is low, and the cushion agent diffuses immediately after injection into the peripheral tissue, thereby causing the protrusion to disappear. The present invention solves these problems by employing a polysaccharide having a pseudoplastic viscosity such as xantham gum, carrageenan, gellan gum, guar gum, locust bean gum, sacran, or the like as a cushion agent.
机译:为了提高内窥镜粘膜切除术的切除效率,可操作性和安全性,常规地采用了一种方法,其中将诸如生理盐水的缓冲剂注入指定用于切除的区域下方的层中,从而使病变抬起并转移。突出(此后简称为“突出”),然后清除病变。使用传统的缓冲剂难以精确地去除期望的区域,因为对突起施加压力趋于引起其变形,突起的程度低,并且缓冲剂在注入周围组织后立即扩散,从而导致突起消失。本发明通过使用具有假塑性粘度的多糖如黄原胶,角叉菜胶,结冷胶,瓜尔豆胶,刺槐豆胶,Sacran等来解决这些问题,作为缓冲剂。

著录项

  • 公开/公告号EP2783709A4

    专利类型

  • 公开/公告日2015-09-30

    原文格式PDF

  • 申请/专利权人 NIHON PHARMACEUTICAL CO. LTD.;

    申请/专利号EP20120851264

  • 发明设计人 NISHIOKA AYUMU;

    申请日2012-11-21

  • 分类号A61L31/00;A61L31/14;

  • 国家 EP

  • 入库时间 2022-08-21 15:05:19

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