首页> 外国专利> METHOD FOR PREPARING WATER EXTRACT OF ASHWAGANDHA LEAVES WHICH HAS ENHANCED ANTI-CANCER ACTIVITY UTILIZING CYCLODEXTRIN, AND PHARMACEUTICAL COMPOSITION CONTAINING ASHWAGANDHA LEAVES

METHOD FOR PREPARING WATER EXTRACT OF ASHWAGANDHA LEAVES WHICH HAS ENHANCED ANTI-CANCER ACTIVITY UTILIZING CYCLODEXTRIN, AND PHARMACEUTICAL COMPOSITION CONTAINING ASHWAGANDHA LEAVES

机译：利用环糊精增强抗癌活性的黄花叶水提取物的制备方法及包含黄花叶的药物组合物

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摘要

The present invention addresses the problem of providing a method for preparing a water extract of ashwagandha (Withania somnifera) leaves, whereby it becomes possible to increase the amounts of withanone and withaferin A, which are active ingredients, in the water extract of ashwagandha leaves. The present invention also addresses the problem of providing a pharmaceutical composition containing ashwagandha leaves in an economically advantageous and simple manner.The present invention relates to: a method for preparing a water extract of ashwagandha leaves, which is characterized by comprising extracting ashwagandha leaves in the presence of cyclodextrin; and a method for enhancing the anti-cancer activity of a water extract of ashwagandha leaves. The present invention also relates to a pharmaceutical composition for treating or preventing cancer, which contains a water extract of ashwagandha leaves. The present invention further relates to a pharmaceutical composition containing a dried powder of ashwagandha leaves and cyclodextrin.

机译：本发明解决了一个问题，即提供了一种制备非洲醉茄叶（ Withania somnifera ）叶的水提取物的方法，从而有可能增加作为活性成分的大黄酮和大黄素A的含量。 ashwagandha叶子的水提取物。本发明还解决了以经济上有利和简单的方式提供含有非洲醉茄叶的药物组合物的问题。本发明涉及一种制备非洲醉参叶水提物的方法，其特征在于，包括在环糊精存在下提取非洲醉参叶。以及用于增强非洲醉茄叶的水提取物的抗癌活性的方法。本发明还涉及用于治疗或预防癌症的药物组合物，该药物组合物包含南非醉茄叶的水提取物。本发明进一步涉及一种药物组合物，该药物组合物包含南非醉茄叶的干粉和环糊精。 展开▼

著录项

公开/公告号WO2015115512A1

专利类型

公开/公告日2015-08-06

原文格式PDF

申请/专利权人 NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY;CYCLOCHEM CO. LTD.;
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申请/专利号WO2015JP52431

发明设计人 WADHWA RENU;KAUL SUNIL;TERAO KEIJI;ISHIDA YOSHIYUKI;
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申请日2015-01-29

分类号A61K36/81;A61K36;A61K47/40;A61P35;

国家 WO

入库时间 2022-08-21 15:05:03

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机译：利用环糊精制备具有增强的抗癌活性的非洲醉茄叶水提取物的方法以及含有非洲醉茄叶的药物组合物

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