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MEST and MIR335/335* as biomarkers of mitochondrial diseases
MEST and MIR335/335* as biomarkers of mitochondrial diseases
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机译:MEST和MIR335 / 335 *作为线粒体疾病的生物标记
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摘要
The present invention concerns an in vitro method of diagnosis or prognosis of a mitochondrial disease by detecting at least one of MEST, microRNA-335 or microRNA-335*, a precursor of said microRNA-335 and microRNA-335* and their use as biomarker of mitochondrial disease. The invention further concerns a ligand specifically binding to at least one of said biomarkers, for use for diagnosing or prognosing of a mitochondrial disease, a pair of primers suitable for amplifying a nucleic acid encoding for at least one of said biomarkers and the kit comprising such ligand and/or pair of primers.
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